| 抗体信息： |
靶标：CDH2
别名：Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDHN;NCAD
背景说明：Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
Swiss Prot：P19022
Gene ID：1000
亚细胞定位：Cell membrane
免疫原：A synthetic peptide of human CDH2
Public Immunogen Range：800-850/906aa
理论分子量：97/100kDa
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