| 宿主： |
Rabbit |
| 抗体信息： |
靶标：E-Cadherin
别名：E-cadherin; anion exchanger protein 3; Arc 1; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 234; CD324; CD324 antigen; CDH1; CDHE; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin; CADH1_HUMAN
背景说明：This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants，at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats，a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric，breast，colorectal，thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation，invasion，and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
Swiss Prot：P12830
Gene ID：999
亚细胞定位：Cell junction，Cell membrane，Endosome，Golgi apparatus，Single-pass type I membrane protein，trans-Golgi network
免疫原：Recombinant protein of human E-Cadherin
Public Immunogen Range：373-622aa
理论分子量：97kDa
|
| 其它标识： |
纯化方法：Affinity purification
储存液：PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件：Store at -20℃. Avoid freeze/thaw cycles.
|
| 基本信息： |
英文名称：Anti-E-Cadherin Polyclonal Antibody
中文名称：上皮钙粘附分子抗体
规格：50ul ; 100ul
宿主：Rabbit
克隆类型：Polyclonal Antibody
亚型：IgG
交叉反应：Human ; Mouse
应用：WB ; IHC
稀释比例：WB 1:500-2000.IHC 1:50-200.
|
| 稀释比例： |
WB 1:500-2000.IHC 1:50-200. |
| 应用： |
WB ; IHC |
| 交叉反应： |
Human ; Mouse |
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