| 抗体信息: |
靶标:CADH2 别名:CDH2;CD325;CDHN;CDw325;NCAD;cadherin-2;N Cadherin
背景说明:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). Swiss Prot:P19022 Gene ID:1000 亚细胞定位:Cell membrane 免疫原:A synthetic peptide of human CADH2 Public Immunogen Range:375-425/906aa 理论分子量:97kDa/99kDa
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