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靶标:CDH3 别名:Cadherin-3, P cadherin, Cadp, Placental cadherin, P-cadherin, AI385538, Pca, Cadherin 3 precursor, Cadherin 3 type 1, Calcium dependent adhesion protein placental, Cadherin, CDH3, CDHP, 7B4 antigen, Cadherin-1, Cadherin-2, Cadherin-4, Cadherin-5, CAM 120/80, CD144, CD324, CD325, Cdh4, CDH5, CDHE, CDHN, CADH3_HUMAN, E-cadherin, Epithelial cadherin, N-cadherin, NCAD, Neural cadherin, P-cadherin, UVO, Uvomorulin, Vascular endothelial cadherin, CDH 3, CDH3, CDH3 protein, CDHP, HJMD, PCAD, Placental cadherin 背景说明:This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). Swiss Prot:P22223 Gene ID:1001 亚细胞定位:Cell membrane Cytoplasm 免疫原:A synthetic peptide of human CDH3 Public Immunogen Range:305-355/829aa 理论分子量:87/91kDa
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