| 抗体信息： |
靶标：CDH4
别名：Cadherin 4, Cadherin4, Cadherin-4 CDH4, R CAD, Retinal Cadherin
背景说明：This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
Swiss Prot：P55283
Gene ID：1002
亚细胞定位：Cell membrane Single-pass type I membrane protein
免疫原：Recombinant protein of human CDH4
Public Immunogen Range：757-916aa
理论分子量：100kDa
|
扫一扫关注我们
