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背景说明:This peptide is a fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser261. Protein phosphorylation plays a key role in vasopressin signaling in renal-collecting duct. Phosphorylation at several AQP2 residues including Ser256 and Ser261, is altered in response to vasopressin. It is possible that both sites are involved in vasopressin-dependent AQP2 trafficking. 该肽是在Ser261处磷酸化的人aquaporin-2(AQP2)的片段。 蛋白质磷酸化在肾脏集合管中的加压素信号传导中起关键作用。 响应于加压素,几个AQP2残基(包括Ser256和Ser261)的磷酸化被改变。 两个位点都可能参与依赖血管加压素的AQP2交易。 In Vitro:未检测 参考文献:[1] Nielsen, S. et al. PNAS 90, 11663 (1993); [2] Hoffert, J. et al. PNAS 103, 7159 (2006).
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