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背景说明:This is amino acids 178 to 191 fragment of the proteolipid protein (PLP), an immunodominant encephalitogenic epitope in SJL mice, one of two major encephalitogenic epitopes. PLP peptide 178 to 191 was compared with another encephalitogenic peptide, 139 to 151. The day of onset of disease induced by PLP 178 to 191 was earlier, but the incidence, severity, and histologic features were indistinguishable. 这是蛋白脂蛋白(PLP)的178至191位氨基酸片段,这是SJL小鼠中的一种免疫性致脑炎性抗原决定簇,是两个主要的致脑炎性抗原决定簇之一。 将PLP 178至191肽与另一种致脑炎肽139至151进行了比较。PLP178至191诱导的疾病发病日期较早,但其发生率,严重程度和组织学特征无法区分。 In Vitro:未检测 参考文献:[1] Greer, J. et al. J. Immunol. 149, 783 (1992); [2] Greer, J. et al. Neurochem. Res. 22, 541-(1997); [3] Bischof, F. et al. J. Immunol. 173, 600 (2004).
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