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背景说明：α-Factor Mating Pheromone, yeast 是一种十三肽，由 S. cerevisiae 的 α 细胞分泌产生，通过 Ste2p 受体起作用。α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.
In Vitro：α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells.
α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability.
参考文献：[1] Lee, BK. et al. J. Biol. Chem. 276, 37950 (2001);
[2] Mayrhofer, S. and S. Poggeler Eukaryot. Cell 4, 661 (2005).
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