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背景说明:A subfragment of the carboxy-terminal propeptide of type I collagen (residues 197-241) was shown to stimulate extracellular matrix biosynthesis in fibroblasts. The pentapeptide KTTKS has been found to be the minimum sequence necessary for this potent stimulation of collagen and fibronectin production in a variety of mesenchymal cells. In Vitro:未检测 参考文献:[1] N.H.Abu Samah and C.M.Heard, Int. J. Cosmet. Sci., 33, 483 (2011); [2] W.-C.Tsai et al., J. Orthop. Res., 25, 1629 (2007); [3] K.Katayama et al., J. Biol. Chem., 268, 9941 (1993).
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