| 生物活性： |
靶点：Fungal
通路：Anti-infection
背景说明：Ciclopirox是抗真菌化合物。
In Vitro：In a study conducted to further elucidate Ciclopirox's mechanism，several Saccharomyces cerevisiae mutants were screened and tested. Results from interpretation of the effects of both the drug treatment and mutation suggested that Ciclopirox may exert its effect by disrupting DNA repair，cell division signals and structures(mitotic spindles)as well as some elements of intracellular transport[2].
数据来源文献：[1]. Niewerth， M.， et al.， Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors， iron metabolism proteins， and drug resistance factors. Antimicrob Agents Chemother， 2003. 47(6): p. 1805-17.
[2]. Leem， S.H.， et al.， The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. Mol Cells， 2003. 15(1): p. 55-61.
|
| 其它标识： |
EC：EINECS 249-577-2
MDL：MFCD00599441
SMILES：CC(C=C(C1CCCCC1)N2O)=CC2=O
InChIKey：SCKYRAXSEDYPSA-UHFFFAOYSA-N
InChI：InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
PubChem CID：2749
|
| 基本信息： |
CAS：29342-05-0
中文名称：环吡酮胺
英文名称：Ciclopirox
别名：环吡酮胺;环吡酮;
分子式：C12H17NO2
分子量：207.27
规格：100mg ; 25mg ; 50mg
溶解性：Soluble in DMSO
纯度：≥98%
外观(性状)：White to light yellow Solid
储存条件：Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
|
| 靶点： |
Fungal |
扫一扫关注我们
