| 生物活性： |
背景说明：The unlabeled phosphopeptide is an excellent substrate for mammalian protein tyrosine phosphatase 1B (Km = 3.9 μM) and Yersinia PTP. The sequence is derived from an autophosphorylation site (Tyr992) of EGFR. The unlabeled peptide is used to assay PTB based on marked fluorescence increase upon the removal of the phosphate group (Em = 305 nm and Ex = 282 nm). 未标记的磷酸肽是哺乳动物蛋白酪氨酸磷酸酶1B（Km=3.9μM）和耶尔森菌PTP的优良底物。序列来源于EGFR的一个自磷酸化位点（Tyr992）。未标记的肽用于基于去除磷酸盐基团后的显著荧光增强（Em=305 nm和Ex=282 nm）来测定PTB。
In Vitro：未检测
参考文献：[1] Ukkola, O. and MJ. Santaniemi, Intern. Med. 251, 467 (2002);
[2] Sarmiento, M. et al. J. Biol. Chem. 273, 26368 (1998);
[3] Zhang, ZY. et al. Anal. Biochem. 211, 7 (1993).
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