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背景说明：Omiganan 是一种阳离子抗菌肽。Omiganan 作为吲哚啶的类似物，对革兰氏阳性菌和革兰氏阴性菌均有抑制作用，对念珠菌也有抑制作用。Omiganan 可以用于酒精鼻和痤疮的研究。
In Vivo：Omiganan results in a statistically significantly reduction in bacterial counts. omiganan reduces the bacterial counts by 3.8 (S. aureus)， 2.2 (S. epidermidis) and 2.3 (C. albicans) log10 CFU/site. Omiganan has rapid bactericidal and fungicidal properties and significant dose-dependent activity against a broad spectrum of infected organisms.
参考文献：[1]. Faccone D， et al. Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates. Eur J Med Chem. 2014;71:31-35.
[2]. Rubinchik E， et al. Antimicrobial and antifungal activities of a novel cationic antimicrobial peptide， omiganan， in experimental skin colonisation models. Int J Antimicrob Agents. 2009;34(5):457-461.
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