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背景说明:FK-13, core sequence of LL-37, is protected from bacterial proteolysis by actin. FK-13 showed activity against HIV-1, EC50 3.4 μM. As removal of the N-terminal phenylalanine leads to inactivation, FKRIVQRIKDFLR corresponds to the minimal anti-HIV region of human LL-37. In Vitro:未检测 参考文献:[1] Dürr, UHN. et al. Biochim Biophys Acta 1758, 1408 (2006); [2] To, KK. et al. Peptides 40,13 (2013).
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