| 抗体信息: |
靶标:SARS-CoV-2 Nucleocapsid 别名:2019-nCoV Nucleocapsid;SARS-CoV-2 Nucleocapsid Protein;SARS-CoV-2 NP;2019-nCoV N 背景说明:Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. Swiss Prot:P0DTC9 Gene ID:43740575 免疫原:Recombinant Protein 理论分子量:46kDa
|