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靶标:SARS-CoV Spike S2 别名:SARS-CoV Spike S2 背景说明:Mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Swiss Prot:P59594 Gene ID:1489668 免疫原:Recombinant protein of SARS-CoV Spike S2 理论分子量:139kDa
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