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靶标:PARP 别名:ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,poly(ADP-ribose) polymerase 1 背景说明:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. Swiss Prot:P09874 Gene ID:142 亚细胞定位:Nucleus nucleolus 免疫原:A synthetic peptide of human PARP Public Immunogen Range:81-390aa 理论分子量:113kDa
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