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背景说明:EA-230 是一种合成寡肽,最初来源于 β-人绒毛膜促性腺激素 (β-hCG) 裂解物。EA-230 具有抗炎作用,可用于脓毒症的研究。 In Vivo:EA-230 (30-50 mg/kg; i.p.; twice daily for four consecutive days) improves survival and attenuate loss of kidney function in a mouse model of renal ischemia/reperfusion injury (IRI) and ischemia-induced delayed graft function after allogenic kidney transplantation. 参考文献:[1]. Gueler F, et al. A novel therapy to attenuate acute kidney injury and ischemic allograft damage after allogenic kidney transplantation in mice. PLoS One. 2015 Jan 24;10(1):e0115709.
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