| 生物活性： |
背景说明：Angiogenin Fragment (108-123) 是血管生成素的 C 末端片段 108-123，可抑制血管生成素的酶促和生物活性。 Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin.
In Vitro：Angiogenin Fragment (108-123) inhibits the initial rate of degradation of tRNA catalyzed by angiogenin in a concentration dependent manner yielding an apparent Ki value of 278 μM. Angiogenin Fragment (108-123) also inhibits nuclease activity of angiogenin when tRNA is the substrate. Furthermore, Angiogenin Fragment (108-123) significantly decreases neovascularization elicited by angiogenin in the chick chorioallantoic membrane assay.
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