| 生物活性： |
背景说明：ACTH（1-13）是ACTH激素的一个片段，它刺激肾上腺皮质和糖皮质激素（例如皮质醇）的分泌。 ACTH（1-13）是melanocortin-3受体的激动剂。 ACTH (1–13) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. ACTH (1–13) is an agonist of the melanocortin-3 receptor.
In Vivo：ACTH (1-13) alone or in combination with met-enkephalin shows potent cytoprotective effects in the model of ethanol induced gastric lesions in rats, and has immunomodulatory effects.
In Vitro：Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease.
参考文献：[1] H.B.Schioth et al., J. Endocrinol., 155, 73 (1997).
|
扫一扫关注我们
