| 生物活性: |
背景说明:A hypothalamic opioid peptide with potent activity in the guinea-pig ileum assay. In Vitro:β-Neo-Endorphin (0-20 μM, 20 h) stimulates wound healing in human keratinocytes. β-Neo-Endorphin (promotes wound healing through activation of the Erk1/2 signaling pathway in human keratinocytes. β-Neo-Endorphin (0-20 μM, 12 h) stimulates keratinocyte migration through activation of metalloproteinase (MMP)-2 and -9. β-Neo-Endorphin (12 h) stimulates migration in the fibroblast. 参考文献:[1] N.Minamino et al., Biochem. Biophys. Res. Commun., 99, 864(1981).
|