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背景说明:c-Myc是c-Myc原癌基因的产物,是一种螺旋-环-螺旋亮氨酸拉链磷蛋白,在细胞增殖、细胞分化和凋亡过程中调节基因转录;该肽是人类c-myc表位。 C-Myc is the product of c-Myc proto oncogene, a helix loop helix leucine zipper phosphoprotein that regulates gene transcription in the process of cell proliferation, differentiation and apoptosis. This peptide is a human c-myc epitope. In Vitro:C-myc plays a critical role in the growth of breast cancer cells. 参考文献:[1] Johnson, G. and L. Hersh, J. Biol. Chem. 269, 7682 (1994); [2] Chou, T. et al. J. Biol. Chem. 270, 18961 (1995); [3] Kato, G. and C. Dang, FASEB J. 6, 3065 (1992).
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