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背景说明：Caloxins是细胞外质膜（PM）Ca2 +泵抑制剂； Caloxin 2A1是一种PM Ca2 +泵抑制剂，选择性结合至细胞外域； 它抑制人红细胞漏液鬼中的Ca2 +-Mg2 +-ATPase； Caloxin 2A1在细胞外部位具有活性，可以简单地外源添加该肽以抑制质膜钙ATPase（PMCA）。 Caloxins are extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 2A1 is a PM Ca2+ pump inhibitor selectively binding to an extracellular domain. It inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts. Caloxin 2A1 is active at an extracellular site, the peptide can simply be added exogenously to inhibit the plasma membrane calcium ATPase (PMCA).
In Vitro：未检测
参考文献：[1] Chaudhary, J. et al. Am. J. Physiol. Cell. Physiol. 280, C1027 (2001);
[2] Chaudhary, J. et al. Am. J. Physiol. Cell. Physiol. 290, C1341 (2006);
[3] Holmes, M. et al. Cell Calcium 33, 241 (2003);
[4] De Luisi, A. and A. Hofer J. Cell Sc. 116, 1527 (2003).
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