| 产品信息： |
背景说明：Clusterin(CLU) is a secreted protein which belongs to the clusterin family.It is also a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis.Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease.Its major form，a heterodimer，is secreted and present in physiological fluids，but truncated forms targeted to the nucleus have also been identified.It is a widely distributed glycoprotein with a wide range of biologic properties.A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis，cystic renal disease，renal tubular injury，neurodegenerative conditions，atherosclerosis，and myocardial infarction.Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling，in apoptotic cell death，and as a stress-induced secreted chaperone protein，amongst others.
来源：Human Cells
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| 其它标识： |
溶剂：Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素：Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
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| 基本信息： |
别名：Clusterin;Apolipoprotein J;Clustrin;Sulfated glycoprotein 2
规格：10ug ; 50ug ; 500ug ; 1mg
外观(性状)：Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度：≥90% as determined by reducing SDS-PAGE.
储存条件：Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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