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靶标:ATP1A1 别名:ATP1A1, alpha 1 Sodium Potassium ATPase,A1A1, AT1A1, AT1A1_HUMAN, Atpa-1, ATPase Na+/K+ transporting alpha 1 polypeptide, ATPase Na+/K+ transporting subunit alpha 1, BC010319, EC 3.6.3.9, MGC3285, MGC38419, MGC51750, Na K ATPase alpha A catalytic polypeptide, Na K ATPase catalytic subunit alpha A protein, Na(+)/K(+) ATPase 1, Na(+)/K(+) ATPase alpha-1 subunit, Na+, K+ ATPase alpha subunit, Na+/K+ ATPase alpha 1 subunit, Na+/K+ ATPase 1, Na,K ATPase alpha 1 subunit, Nkaa1b, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump 1, Sodium pump subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1 背景说明:The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Swiss Prot:P05023 Gene ID:476 亚细胞定位:Cell membrane Melanosome Multi-pass membrane protein 免疫原:A synthetic peptide of human ATP1A1 Public Immunogen Range:240-290/1023aa 理论分子量:74/110/113kDa
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