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靶标:COX4I1 别名:COX IV-1,COX4,COX4-1,COXIV,COXIV-1,cytochrome c oxidase subunit 4I1 背景说明:Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiRatory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiRatory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. Swiss Prot:P13073 Gene ID:1327 亚细胞定位:Cytoplasm Nucleus 免疫原:Recombinant protein of human COX4I1 Public Immunogen Range:1-100aa 理论分子量:20kDa
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