| 宿主： |
Mouse |
| 抗体信息： |
靶标：M6A
别名：6-N-Methyladenoside;m6A;N6-methyladenosine;M6A
背景说明：m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed writerssuch as METTL3 and METTL14, and can be reversed by demethylases that serve as erasers such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy.
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| 其它标识： |
纯化方法：Protein A purification
储存液：PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
储存条件：Store at -20℃. Avoid freeze / thaw cycles.
|
| 基本信息： |
英文名称：Anti-M6A Monoclonal Antibody
规格：50ul ; 100ul
宿主：Mouse
克隆类型：Monoclonal antibody
亚型：IgG3
交叉反应：M6A ; Mouse ; Rat ; Human
应用：ELISA ; RIP ; DB ; IHC
稀释比例：IHC 1:2000-8000. RIP 1:1000-4000. DB 1:1000-4000. ELISA 1:2000-20000.
|
| 稀释比例： |
IHC 1:2000-8000. RIP 1:1000-4000. DB 1:1000-4000. ELISA 1:2000-20000. |
| 应用： |
ELISA ; RIP ; DB ; IHC |
| 交叉反应： |
M6A ; Mouse ; Rat ; Human |
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