| 抗体信息： |
靶标：VCL
别名：CMD1W;CMH15;HEL114;MV;MVCL;Metavinculin;Vinculin
背景说明：Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Swiss Prot：P18206
Gene ID：7414
亚细胞定位：Cell junction Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein adherens junction cytoskeleton focal adhesion
免疫原：A synthetic peptide of human VCL
Public Immunogen Range：767-1066aa
理论分子量：124/117/25kDa
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