| 区间范围： |
1-185aa |
| 基因名： |
GREM1 |
| 标签信息： |
With a 6×His tag at the N/C-terminus. |
| 产品信息： |
Swiss Prot：O60565
Gene ID：26585
交叉反应：Human Mouse Rat (Chicken)
分子量：20.7kDa
区间范围：1-185aa
背景说明：This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用：Immunology research
来源：E.coli
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| 其它标识： |
纯化方法：NI-NTA affinity purification
溶剂：Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素：Not measured
生物活性：NO
标签信息：With a 6×His tag at the N/C-terminus.
|
| 基本信息： |
基因名：GREM1
别名：C15DUPq;CKTSF1B1;CRAC1;CRCS4;DAND2;DRM;DUP15q;GREMLIN;HMPS;HMPS1;IHG-2;MPSH;PIG2;gremlin-1
全名：gremlin 1，cysteine knot superfamily，homolog (Xenopus laevis)
英文名称：Recombinant human GREM1 protein
中文名称：/
规格：10ug ; 50ug ; 100ug ; 1mg
外观(性状)：Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度：≥85% by SDS-PAGE.
储存条件：Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件：The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度：1mg/ml by SDS-PAGE.
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