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背景说明：这是逆转录酶（RT）表位（Pol残基476-484）； 在HIV-1 RT中，该肽似乎是显性的HLA A * 0201限制性表位； 用于调查HIV-1从CTL逃逸的可能机制； IV9是在HIV-1感染的细胞系中加工并呈递的实际表位。
This is a reverse transcriptase (RT) epitope (Pol residues 476-484). Within HIV-1 RT the peptide appears to be the dominant HLA A * 0201-restricted epitope. Was used to investigate possible mechanisms behind HIV-1 escape from CTL. IV9 is the actual epitope processed and presented in HIV-1-infected cell lines.
In Vitro：未检测
参考文献：[1] Sewell, A. et al. The Journal of Immunology 162, 7075 (1999);
[2] Jamieson, B. et al. The Journal of Immunology 171, 5372 (2003);
[3] Brander, C. et al. J. Clin. Invest 101, 2559 (1998);
[4] Goulder,P. et al. J. Exp. Med 185, 1423 (1997).
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